Opportunities - Development and evaluation of a patient-centered electronic outcome assessment (strokePRO) system for acute stroke trials

Development and evaluation of a patient-centered electronic outcome assessment (strokePRO) system for acute stroke trials
University of Calgary

Patient-reported outcomes (PROs) are reports from patients about their own health, quality of life, or functional status associated with the healthcare or treatment they have received. Unfortunately, there is limited use of PROs in acute stroke trials with patients who have recently suffered a stroke. These types of stroke trials typically look at measures of functional disability, and exclude important aspects such as cognitive function, mood, mental health, anxiety, and fatigue, amongst others.
Electronic clinical outcome assessment (eCOA) systems offer a simpler and faster method of assessing patients and collecting PROs in stroke trials. There is an abundance of literature that suggests that use of eCOA systems in acute stroke trials can support increased diversity in patient recruitment and retention, better data quality, improved efficiency, and reduce missing data. This project addresses the gaps in this area by first understanding patient’s experiences in previous stroke trials, priorities about what matters to them, preferences about the method of electronic outcome assessment, and barriers to using these systems. This knowledge will inform the design and development of an electronic platform, called strokePRO, which aims to shift how clinical outcomes are collected and assessed in acute stroke trials.
The strokePRO tool will be a web-based app that will improve the quality of data in stroke research by being a more simple and reliable way of collecting and analyzing PROs. Furthermore, strokePRO will boost the recruitment and retention of patients in acute stroke trials by eliminating barriers that are faced by equity-deserving groups (e.g., transportation to visits and any other indirect costs) and by reducing trial costs and burden for stroke investigators and neurologists.

Roles and Responsibilities
We hope to invite up to 5 patient research partners with lived experience of stroke and/or stroke patient caregivers to join our study steering committee. In this committee, patient partners would share essential insights and feedback on study design, participant recruitment, conduct, and implementation of the strokePRO tool. We hope to have a group of patient partners that is representative of the diverse communities and populations that make up Canada.

Time Commitment
The project is expected to last 3 years, with funding starting in February 2024, however, we ask for a commitment of at least 1 year with the opportunity to continue after each year is completed. We expect to host hour-long meetings bi-annually for the steering committee, with the opportunity for additional meetings where we ask for further patient partner feedback.

Compensation at a rate of $25/hour spent will be offered to patient partners.
This is an online opportunity (meetings will be held online via Zoom) so there are no expenses anticipated for travel, parking, etc.

For more information or to apply please contact:
1. Principal Investigator - Dr. Tolulope Sajobi

2. Study Coordinator - Nirav Bhagat