Opportunities - The POMELO (Prevention of MusclE Loss in Osteoarthritis) Trial _Patient-advisory team members

The POMELO (Prevention of MusclE Loss in Osteoarthritis) Trial

Patient-advisory team members
University of Alberta

This opportunity is looking for 2 individuals who have experience of living with knee arthritis and a larger body size [a body mass index (BMI) ≥35 kg/m2], specifically males, or individuals of any gender who identify as indigenous, metis, or of non-caucasian ethnic or racial heritage.

Interested individuals will join the patient-advisory team guiding our pilot clinical trial, funded by the Arthritis Society. Patient-advisory team members will consult on study activities through quarterly meetings held online, and receive an honorarium for their contribution.


The best way to treat advanced knee osteoarthritis (OA) in Canadians with a larger body size (BMI ≥35 kg/m2) is unclear. These individuals are less likely to be referred for surgical arthritis treatment due to a higher risk of infection after surgery. They are often told to lose weight even though it is uncertain if weight-loss is beneficial. Further, weight loss could increase the risk for muscle loss and development of sarcopenia. Therefore, alternative approaches to manage advanced knee OA for this clinical population are needed. The POMELO (Prevention of MusclE Loss in Osteoarthritis) trial will examine a personalized intervention (including nutrition, resistance exercise, and self-management support) in comparison to usual care. The intervention is designed to improve physical function, muscle mass, arthritis symptoms and overall health. The POMELO trial will test the acceptability and effectiveness of this treatment approach by examining study participants randomly assigned to receive either the intervention or usual care. This trial has been funded by the Arthritis Society, and will be conducted in 2021-2024.

Roles and Responsibilities

Members of the patient-advisory team will advise on topics and issues regarding the POMELO trial. This team will work with the lead investigators and support their efforts to ensure the patient and public perspective is respected and incorporated in trial activities. This includes providing general guidance and consultation, reviewing study documents or materials, and advising on strategies for participant enrollment, and sharing of study findings.

Time Commitment

Attend quarterly meetings held online through zoom video conferencing on a weekday evening. Individuals are expected to review meeting materials ahead of time and participate in meeting discussions. The time commitment is 3 hours per quarter, or 12 hours total per year. This project starts in April 2021.


Honorarium of $50/hour, to a maximum of 3 hours per quarter, or 12 hours per year. No travel is required, and all meetings will be held online.

For more information, please contact:

Dr. Kristine Godziuk     godziuk@ualberta.ca